Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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thiIThiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (391 aa)    
Predicted Functional Partners:
FMG_0558
Iron-sulfur cofactor synthesis protein.
 
 0.994
FMG_1587
Iron-sulfur cofactor synthesis protein.
  
 0.971
FMG_0064
Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
     
 0.933
FMG_0065
Molybdopterin/thiamine biosynthesis protein.
     
  0.900
FMG_0560
Putative cytoplasmic membrane protein LemA family.
       0.781
FMG_0561
Conserved hypothetical protein.
       0.755
FMG_0664
Putative rRNA methylase; SUN family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
    0.722
FMG_0776
Fe-S oxidoreductase.
   
  
 0.563
FMG_0556
Conserved hypothetical protein.
       0.547
FMG_0557
Hypothetical protein.
       0.547
Your Current Organism:
Finegoldia magna ATCC 29328
NCBI taxonomy Id: 334413
Other names: F. magna ATCC 29328, Finegoldia magna str. ATCC 29328, Finegoldia magna strain ATCC 29328
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