| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FMG_0385 | FMG_1153 | FMG_0385 | FMG_1153 | Pyruvate/ferredoxin oxidoreductase. | Conserved hypothetical protein. | 0.410 |
| FMG_0385 | pyrD | FMG_0385 | FMG_0725 | Pyruvate/ferredoxin oxidoreductase. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.652 |
| FMG_0385 | pyrK | FMG_0385 | FMG_0724 | Pyruvate/ferredoxin oxidoreductase. | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.646 |
| FMG_0721 | FMG_0722 | FMG_0721 | FMG_0722 | Aspartate carbamoyltransferase regulatory subunit. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.981 |
| FMG_0721 | pyrB | FMG_0721 | FMG_0720 | Aspartate carbamoyltransferase regulatory subunit. | Aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| FMG_0721 | pyrD | FMG_0721 | FMG_0725 | Aspartate carbamoyltransferase regulatory subunit. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.901 |
| FMG_0721 | pyrE | FMG_0721 | FMG_0726 | Aspartate carbamoyltransferase regulatory subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.809 |
| FMG_0721 | pyrF | FMG_0721 | FMG_0723 | Aspartate carbamoyltransferase regulatory subunit. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.951 |
| FMG_0721 | pyrK | FMG_0721 | FMG_0724 | Aspartate carbamoyltransferase regulatory subunit. | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.851 |
| FMG_0722 | FMG_0721 | FMG_0722 | FMG_0721 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase regulatory subunit. | 0.981 |
| FMG_0722 | FMG_1015 | FMG_0722 | FMG_1015 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Xanthine/uracil permease family protein. | 0.695 |
| FMG_0722 | FMG_1065 | FMG_0722 | FMG_1065 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Uracil permease. | 0.924 |
| FMG_0722 | pyrB | FMG_0722 | FMG_0720 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| FMG_0722 | pyrD | FMG_0722 | FMG_0725 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.999 |
| FMG_0722 | pyrE | FMG_0722 | FMG_0726 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.981 |
| FMG_0722 | pyrF | FMG_0722 | FMG_0723 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.979 |
| FMG_0722 | pyrK | FMG_0722 | FMG_0724 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.998 |
| FMG_1015 | FMG_0722 | FMG_1015 | FMG_0722 | Xanthine/uracil permease family protein. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.695 |
| FMG_1015 | pyrB | FMG_1015 | FMG_0720 | Xanthine/uracil permease family protein. | Aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.746 |
| FMG_1015 | pyrD | FMG_1015 | FMG_0725 | Xanthine/uracil permease family protein. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.709 |