| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FMG_0345 | murJ | FMG_0345 | FMG_0859 | Soluble lytic murein transglycosylase. | Putative virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.404 |
| FMG_0613 | murA | FMG_0613 | FMG_1500 | Cell division protein; Penicillin-binding protein 2 homolog. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.816 |
| FMG_0613 | murC | FMG_0613 | FMG_0421 | Cell division protein; Penicillin-binding protein 2 homolog. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.859 |
| FMG_0613 | murJ | FMG_0613 | FMG_0859 | Cell division protein; Penicillin-binding protein 2 homolog. | Putative virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.497 |
| FMG_0856 | FMG_0857 | FMG_0856 | FMG_0857 | Conserved hypothetical protein. | Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family. | 0.783 |
| FMG_0856 | aspS | FMG_0856 | FMG_0858 | Conserved hypothetical protein. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.814 |
| FMG_0856 | glyA | FMG_0856 | FMG_0855 | Conserved hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.792 |
| FMG_0856 | murJ | FMG_0856 | FMG_0859 | Conserved hypothetical protein. | Putative virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.422 |
| FMG_0857 | FMG_0856 | FMG_0857 | FMG_0856 | Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family. | Conserved hypothetical protein. | 0.783 |
| FMG_0857 | aspS | FMG_0857 | FMG_0858 | Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.783 |
| FMG_0857 | glyA | FMG_0857 | FMG_0855 | Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.780 |
| FMG_0857 | murJ | FMG_0857 | FMG_0859 | Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family. | Putative virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.422 |
| FMG_0860 | murJ | FMG_0860 | FMG_0859 | Conserved hypothetical protein. | Putative virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.546 |
| aspS | FMG_0856 | FMG_0858 | FMG_0856 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Conserved hypothetical protein. | 0.814 |
| aspS | FMG_0857 | FMG_0858 | FMG_0857 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family. | 0.783 |
| aspS | glyA | FMG_0858 | FMG_0855 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.835 |
| aspS | murJ | FMG_0858 | FMG_0859 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Putative virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.458 |
| glyA | FMG_0856 | FMG_0855 | FMG_0856 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Conserved hypothetical protein. | 0.792 |
| glyA | FMG_0857 | FMG_0855 | FMG_0857 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family. | 0.780 |
| glyA | aspS | FMG_0855 | FMG_0858 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.835 |