| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FMG_0722 | FMG_1015 | FMG_0722 | FMG_1015 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Xanthine/uracil permease family protein. | 0.695 |
| FMG_0722 | purD | FMG_0722 | FMG_1359 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family. | 0.663 |
| FMG_0722 | pyrB | FMG_0722 | FMG_0720 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| FMG_0722 | pyrD | FMG_0722 | FMG_0725 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.999 |
| FMG_0722 | pyrE | FMG_0722 | FMG_0726 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.981 |
| FMG_0722 | pyrF | FMG_0722 | FMG_0723 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.979 |
| FMG_0722 | pyrK | FMG_0722 | FMG_0724 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.998 |
| FMG_1015 | FMG_0722 | FMG_1015 | FMG_0722 | Xanthine/uracil permease family protein. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.695 |
| FMG_1015 | FMG_1016 | FMG_1015 | FMG_1016 | Xanthine/uracil permease family protein. | Carbamate kinase; Belongs to the carbamate kinase family. | 0.573 |
| FMG_1015 | gatA | FMG_1015 | FMG_0571 | Xanthine/uracil permease family protein. | glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.576 |
| FMG_1015 | purD | FMG_1015 | FMG_1359 | Xanthine/uracil permease family protein. | Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family. | 0.856 |
| FMG_1015 | pyrB | FMG_1015 | FMG_0720 | Xanthine/uracil permease family protein. | Aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.746 |
| FMG_1015 | pyrD | FMG_1015 | FMG_0725 | Xanthine/uracil permease family protein. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.709 |
| FMG_1015 | pyrE | FMG_1015 | FMG_0726 | Xanthine/uracil permease family protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.722 |
| FMG_1015 | pyrF | FMG_1015 | FMG_0723 | Xanthine/uracil permease family protein. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.731 |
| FMG_1015 | pyrK | FMG_1015 | FMG_0724 | Xanthine/uracil permease family protein. | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.653 |
| FMG_1015 | xpt | FMG_1015 | FMG_1031 | Xanthine/uracil permease family protein. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.945 |
| FMG_1016 | FMG_1015 | FMG_1016 | FMG_1015 | Carbamate kinase; Belongs to the carbamate kinase family. | Xanthine/uracil permease family protein. | 0.573 |
| FMG_1016 | pyrB | FMG_1016 | FMG_0720 | Carbamate kinase; Belongs to the carbamate kinase family. | Aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.835 |
| gatA | FMG_1015 | FMG_0571 | FMG_1015 | glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | Xanthine/uracil permease family protein. | 0.576 |