STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (273 aa)    
Predicted Functional Partners:
nadE
NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.950
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.944
FMG_0296
Transcriptional regulator Sir2 family.
  
 
 0.919
FMG_1026
Putative 23S RNA-specific pseudouridylate synthase.
  
  
 0.609
argR
Transcriptional regulator ArgR family; Regulates arginine biosynthesis genes.
 
  
 0.561
FMG_0839
Putative hemolysin.
  
  
 0.525
aroK
Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family.
   
 
 0.524
ffh
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
    0.440
FMG_0856
Conserved hypothetical protein.
  
     0.432
FMG_0818
3-oxoacyl-[acyl-carrier protein] reductase.
 
  
 0.417
Your Current Organism:
Finegoldia magna ATCC 29328
NCBI taxonomy Id: 334413
Other names: F. magna ATCC 29328, Finegoldia magna str. ATCC 29328, Finegoldia magna strain ATCC 29328
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.