FMG_1252 protein (Finegoldia magna ATCC 29328)

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Score

FMG_1252

Low specificity L-threonine aldolase. (338 aa)

Predicted Functional Partners:

thrB

0.960

glyA

0.936

FMG_1264

0.929

gcvPA

0.916

gcvPB

0.916

FMG_1253

0.552

Your Current Organism:

Finegoldia magna ATCC 29328

NCBI taxonomy Id: 334413
Other names: F. magna ATCC 29328, Finegoldia magna str. ATCC 29328, Finegoldia magna strain ATCC 29328

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FMG_1252	FMG_1253	FMG_1252	FMG_1253	Low specificity L-threonine aldolase.	Conserved hypothetical protein.	0.552
FMG_1252	FMG_1264	FMG_1252	FMG_1264	Low specificity L-threonine aldolase.	Threonine synthase.	0.929
FMG_1252	gcvPA	FMG_1252	FMG_0464	Low specificity L-threonine aldolase.	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.916
FMG_1252	gcvPB	FMG_1252	FMG_0465	Low specificity L-threonine aldolase.	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.916
FMG_1252	glyA	FMG_1252	FMG_0855	Low specificity L-threonine aldolase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.936
FMG_1252	thrB	FMG_1252	FMG_0320	Low specificity L-threonine aldolase.	Threonine synthase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.	0.960
FMG_1253	FMG_1252	FMG_1253	FMG_1252	Conserved hypothetical protein.	Low specificity L-threonine aldolase.	0.552
FMG_1264	FMG_1252	FMG_1264	FMG_1252	Threonine synthase.	Low specificity L-threonine aldolase.	0.929
FMG_1264	thrB	FMG_1264	FMG_0320	Threonine synthase.	Threonine synthase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.	0.980
gcvPA	FMG_1252	FMG_0464	FMG_1252	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Low specificity L-threonine aldolase.	0.916
gcvPA	gcvPB	FMG_0464	FMG_0465	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.999
gcvPA	glyA	FMG_0464	FMG_0855	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.978
gcvPB	FMG_1252	FMG_0465	FMG_1252	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Low specificity L-threonine aldolase.	0.916
gcvPB	gcvPA	FMG_0465	FMG_0464	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.999
gcvPB	glyA	FMG_0465	FMG_0855	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.984
glyA	FMG_1252	FMG_0855	FMG_1252	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Low specificity L-threonine aldolase.	0.936
glyA	gcvPA	FMG_0855	FMG_0464	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.978
glyA	gcvPB	FMG_0855	FMG_0465	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glycine dehydrogenase subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.984
glyA	thrB	FMG_0855	FMG_0320	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Threonine synthase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.	0.536
thrB	FMG_1252	FMG_0320	FMG_1252	Threonine synthase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.	Low specificity L-threonine aldolase.	0.960