Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
purFPhosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (448 aa)    
Predicted Functional Partners:
purD
Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family.
 
 0.999
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase.
 
 
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
  
 0.997
FMG_1358
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.996
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.994
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
 
 
 0.989
purE
Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
  
 0.979
FMG_1149
Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 0.941
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
  
0.914
FMG_0992
Glutamine synthase type III; Belongs to the glutamine synthetase family.
    
  0.904
Your Current Organism:
Finegoldia magna ATCC 29328
NCBI taxonomy Id: 334413
Other names: F. magna ATCC 29328, Finegoldia magna str. ATCC 29328, Finegoldia magna strain ATCC 29328
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