Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FMG_1616Conserved hypothetical protein. (162 aa)    
Predicted Functional Partners:
FMG_1619
Chromosome partitioning protein ParB homolog; Belongs to the ParB family.
  
 
 0.835
FMG_1620
Chromosome partitioning protein ParA homolog.
  
  
 0.827
cinA
Competence-damage inducible protein; Belongs to the CinA family.
       0.815
FMG_1618
Methenyl tetrahydrofolate cyclohydrolase.
       0.793
FMG_1617
Aminotransferase required for NAD biosynthesis.
       0.782
FMG_1615
Phosphotransacetylase.
       0.745
FMG_1614
Hypothetical protein.
       0.701
FMG_1613
Conserved hypothetical protein.
       0.607
FMG_1028
Putative penicillin-binding protein.
 
     0.529
gyrB
DNA gyrase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.503
Your Current Organism:
Finegoldia magna ATCC 29328
NCBI taxonomy Id: 334413
Other names: F. magna ATCC 29328, Finegoldia magna str. ATCC 29328, Finegoldia magna strain ATCC 29328
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