STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FVEG_01009Bloom syndrome protein. (1669 aa)    
Predicted Functional Partners:
FVEG_08135
Exonuclease 1.
  
 0.934
FVEG_05391
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.916
FVEG_01282
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
  
 0.901
FVEG_02845
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 0.876
FVEG_14962
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.865
FVEG_09775
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.858
FVEG_01259
Crossover junction endonuclease MUS81.
   
 0.856
FVEG_00713
DNA repair protein RAD57.
  
 0.853
FVEG_02883
DNA repair and recombination protein RAD52.
   
 0.846
FVEG_06331
Replication factor A2.
   
 0.830
Your Current Organism:
Fusarium verticillioides
NCBI taxonomy Id: 334819
Other names: F. verticillioides 7600, Fusarium verticillioides 7600, Gibberella moniliformis 7600
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.