STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000000026Cyclin F. (784 aa)    
Predicted Functional Partners:
CCH79_00002477
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.973
CCH79_00019068
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.968
CCH79_00005303
WD_REPEATS_REGION domain-containing protein.
   
 0.947
ENSGAFP00000007624
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.922
CCH79_00009260
Uncharacterized protein.
   
 0.919
ENSGAFP00000032326
Extra spindle pole bodies like 1, separase.
   
  
 0.878
CCH79_00017306
CDT1 domain-containing protein.
   
 0.873
ENSGAFP00000028974
Ubiquitin-conjugating enzyme E2C.
   
 0.850
CCH79_00013703
RING-type domain-containing protein.
    
 0.845
CCH79_00009563
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.844
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.