Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
CCH79_00012022Ubiquitin carboxyl-terminal hydrolase. (811 aa)    
Predicted Functional Partners:
USP16
Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
  
  
 
0.905
CCH79_00002926
Uncharacterized protein.
    
 0.898
ENSGAFP00000011060
annotation not available
    
  0.777
CCH79_00008829
OTU domain-containing protein.
      
 0.717
CCH79_00012197
NARG2_C domain-containing protein.
      
 0.714
CCH79_00008494
BTB domain-containing protein.
      
 0.706
CCH79_00007766
Uncharacterized protein.
      
 0.701
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
      
 0.696
ENSGAFP00000006843
Interleukin 10.
      
 0.685
CCH79_00000140
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
  0.650
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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