CCH79_00017792 protein (Gambusia affinis) - STRING interaction network

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Score

CCH79_00017792

Protein kinase domain-containing protein. (559 aa)

Predicted Functional Partners:

CCH79_00012961

0.783

DCAF7

0.743

CCH79_00003653

0.703

CCH79_00017765

0.691

CCH79_00013840

0.651

ENSGAFP00000025610

0.628

CCH79_00010612

0.628

CCH79_00004546

0.627

ENSGAFP00000021072

0.610

ENSGAFP00000010268

0.599

Your Current Organism:

Gambusia affinis

NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCH79_00003653	CCH79_00010612	ENSGAFP00000003434	ENSGAFP00000028353	Non-specific serine/threonine protein kinase.	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	0.914
CCH79_00003653	CCH79_00012961	ENSGAFP00000003434	ENSGAFP00000008062	Non-specific serine/threonine protein kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.995
CCH79_00003653	CCH79_00017765	ENSGAFP00000003434	ENSGAFP00000030946	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.926
CCH79_00003653	CCH79_00017792	ENSGAFP00000003434	ENSGAFP00000001227	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.703
CCH79_00003653	ENSGAFP00000010268	ENSGAFP00000003434	ENSGAFP00000010268	Non-specific serine/threonine protein kinase.	MDM4 regulator of p53.	0.872
CCH79_00003653	ENSGAFP00000021072	ENSGAFP00000003434	ENSGAFP00000021072	Non-specific serine/threonine protein kinase.	Ribosomal protein S27a.	0.655
CCH79_00003653	ENSGAFP00000025610	ENSGAFP00000003434	ENSGAFP00000025610	Non-specific serine/threonine protein kinase.	Tumor protein p63.	0.914
CCH79_00004546	CCH79_00017792	ENSGAFP00000025381	ENSGAFP00000001227	Uncharacterized protein.	Protein kinase domain-containing protein.	0.627
CCH79_00010612	CCH79_00003653	ENSGAFP00000028353	ENSGAFP00000003434	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Non-specific serine/threonine protein kinase.	0.914
CCH79_00010612	CCH79_00012961	ENSGAFP00000028353	ENSGAFP00000008062	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.884
CCH79_00010612	CCH79_00013840	ENSGAFP00000028353	ENSGAFP00000019622	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Peptidyl-prolyl cis-trans isomerase.	0.742
CCH79_00010612	CCH79_00017765	ENSGAFP00000028353	ENSGAFP00000030946	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Uncharacterized protein.	0.954
CCH79_00010612	CCH79_00017792	ENSGAFP00000028353	ENSGAFP00000001227	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Protein kinase domain-containing protein.	0.628
CCH79_00010612	ENSGAFP00000010268	ENSGAFP00000028353	ENSGAFP00000010268	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	MDM4 regulator of p53.	0.869
CCH79_00010612	ENSGAFP00000021072	ENSGAFP00000028353	ENSGAFP00000021072	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Ribosomal protein S27a.	0.843
CCH79_00012961	CCH79_00003653	ENSGAFP00000008062	ENSGAFP00000003434	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Non-specific serine/threonine protein kinase.	0.995
CCH79_00012961	CCH79_00010612	ENSGAFP00000008062	ENSGAFP00000028353	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	0.884
CCH79_00012961	CCH79_00013840	ENSGAFP00000008062	ENSGAFP00000019622	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Peptidyl-prolyl cis-trans isomerase.	0.888
CCH79_00012961	CCH79_00017765	ENSGAFP00000008062	ENSGAFP00000030946	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Uncharacterized protein.	0.999
CCH79_00012961	CCH79_00017792	ENSGAFP00000008062	ENSGAFP00000001227	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Protein kinase domain-containing protein.	0.783