Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00012029ENTH domain-containing protein. (226 aa)    
Predicted Functional Partners:
CCH79_00009024
Uncharacterized protein.
   
 0.967
CCH79_00005153
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.897
ENSGAFP00000007177
Intersectin 2a.
    
 0.872
CCH79_00006118
Uncharacterized protein.
    
 0.872
ENSGAFP00000012493
Intersectin 2b.
    
 0.872
CCH79_00015780
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 0.868
CCH79_00013256
Protein kinase domain-containing protein.
    
 0.861
CCH79_00017211
Uncharacterized protein.
    
 0.811
ENSGAFP00000005931
annotation not available
    
 0.811
ENSGAFP00000005965
annotation not available
    
 0.811
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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