Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00001345Protein kinase domain-containing protein. (1137 aa)    
Predicted Functional Partners:
CCH79_00018142
GDNF domain-containing protein.
    
 0.998
ENSGAFP00000014062
annotation not available
    
 0.998
CCH79_00000900
TGF_BETA_2 domain-containing protein.
    
 0.998
CCH79_00014736
Uncharacterized protein.
    
 0.993
CCH79_00009627
TGF_BETA_2 domain-containing protein.
    
 0.993
ENSGAFP00000011510
annotation not available
    
 0.967
CCH79_00011609
IRS-type PTB domain-containing protein.
    
  0.965
CCH79_00020153
Phosphoinositide phospholipase C.
    
 0.957
CCH79_00013516
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.957
CCH79_00006731
Phosphoinositide phospholipase C.
    
 0.957
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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