Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00009754BZIP domain-containing protein. (111 aa)    
Predicted Functional Partners:
CCH79_00009752
KID domain-containing protein.
 
   
  0.924
ENSGAFP00000015861
E1A binding protein p300 b.
    
 0.897
CCH79_00018727
Uncharacterized protein.
    
 0.815
CCH79_00014256
Uncharacterized protein.
    
 0.815
CCH79_00012961
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.800
CCH79_00002145
Ribosomal protein S6 kinase.
   
 0.760
CCH79_00007983
Non-specific serine/threonine protein kinase.
   
 0.760
ENSGAFP00000006897
MAPK activated protein kinase 2b.
    
 0.734
CCH79_00007436
Uncharacterized protein.
    
 0.714
CCH79_00009546
Uncharacterized protein.
    
 0.709
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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