STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000001404DEXH (Asp-Glu-X-His) box polypeptide 58. (675 aa)    
Predicted Functional Partners:
CCH79_00002824
Uncharacterized protein.
  
0.984
CCH79_00014979
USP domain-containing protein.
   
 
 0.964
CCH79_00013697
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.930
CCH79_00001420
RING-type domain-containing protein.
    
 0.923
CCH79_00006955
Uncharacterized protein.
    
 0.919
CCH79_00015352
Uncharacterized protein.
    
 0.916
CCH79_00002702
Uncharacterized protein.
   
 0.915
CCH79_00012221
Uncharacterized protein.
   
 0.915
CCH79_00008724
Uncharacterized protein.
   
 0.915
CCH79_00008922
Uncharacterized protein.
    
 0.914
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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