CCH79_00010690 protein (Gambusia affinis) - STRING interaction network

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CCH79_00010690

AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (787 aa)

Predicted Functional Partners:

CCH79_00017305

0.977

ADK

0.968

ENSGAFP00000000816

0.965

IMPDH-2

0.965

GMPR-2

0.965

CCH79_00002123

0.965

ENSGAFP00000025098

0.965

ADSSL1

0.965

CCH79_00004961

0.961

CCH79_00005816

0.957

Your Current Organism:

Gambusia affinis

NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADK	ADSSL1	ENSGAFP00000008168	ENSGAFP00000025973	Adenosine kinase.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.798
ADK	CCH79_00002123	ENSGAFP00000008168	ENSGAFP00000019687	Adenosine kinase.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.798
ADK	CCH79_00004961	ENSGAFP00000008168	ENSGAFP00000012905	Adenosine kinase.	MGS domain-containing protein.	0.854
ADK	CCH79_00005816	ENSGAFP00000008168	ENSGAFP00000001616	Adenosine kinase.	Pribosyltran domain-containing protein.	0.564
ADK	CCH79_00010690	ENSGAFP00000008168	ENSGAFP00000001450	Adenosine kinase.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.968
ADK	CCH79_00017305	ENSGAFP00000008168	ENSGAFP00000015165	Adenosine kinase.	Pribosyltran domain-containing protein.	0.986
ADK	ENSGAFP00000000816	ENSGAFP00000008168	ENSGAFP00000000816	Adenosine kinase.	Adenylosuccinate synthase 2.	0.798
ADK	ENSGAFP00000025098	ENSGAFP00000008168	ENSGAFP00000025098	Adenosine kinase.	IMP (inosine 5'-monophosphate) dehydrogenase 1b.	0.567
ADK	GMPR-2	ENSGAFP00000008168	ENSGAFP00000015592	Adenosine kinase.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.567
ADK	IMPDH-2	ENSGAFP00000008168	ENSGAFP00000007181	Adenosine kinase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.567
ADSSL1	ADK	ENSGAFP00000025973	ENSGAFP00000008168	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenosine kinase.	0.798
ADSSL1	CCH79_00002123	ENSGAFP00000025973	ENSGAFP00000019687	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.951
ADSSL1	CCH79_00004961	ENSGAFP00000025973	ENSGAFP00000012905	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	MGS domain-containing protein.	0.986
ADSSL1	CCH79_00005816	ENSGAFP00000025973	ENSGAFP00000001616	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Pribosyltran domain-containing protein.	0.966
ADSSL1	CCH79_00010690	ENSGAFP00000025973	ENSGAFP00000001450	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.965
ADSSL1	CCH79_00017305	ENSGAFP00000025973	ENSGAFP00000015165	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Pribosyltran domain-containing protein.	0.645
ADSSL1	ENSGAFP00000000816	ENSGAFP00000025973	ENSGAFP00000000816	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthase 2.	0.951
ADSSL1	ENSGAFP00000025098	ENSGAFP00000025973	ENSGAFP00000025098	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	IMP (inosine 5'-monophosphate) dehydrogenase 1b.	0.981
ADSSL1	GMPR-2	ENSGAFP00000025973	ENSGAFP00000015592	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.981
ADSSL1	IMPDH-2	ENSGAFP00000025973	ENSGAFP00000007181	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.981