STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000001517Inhibitor of Bruton agammaglobulinemia tyrosine kinase. (1345 aa)    
Predicted Functional Partners:
CCH79_00003710
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.804
CCH79_00005254
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.804
CCH79_00019068
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.788
CCH79_00001358
Cullin domain-containing protein; Belongs to the cullin family.
   
 0.748
CCH79_00011241
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
   0.669
CCH79_00014475
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
   0.669
CCH79_00002878
Uncharacterized protein.
   
 0.666
CCH79_00001659
Uncharacterized protein.
    
 0.633
ENSGAFP00000017278
Ankyrin repeat domain 9.
    
 0.616
CCH79_00012918
Uncharacterized protein.
   
 0.590
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.