Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000001540Adenomatosis polyposis coli down-regulated 1-like. (514 aa)    
Predicted Functional Partners:
CCH79_00016579
Uncharacterized protein.
    
 0.927
CCH79_00017423
Uncharacterized protein.
    
 0.927
APCDD1
APC down-regulated 1.
  
  
 
0.904
CCH79_00017666
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.748
CCH79_00014844
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.748
ENSGAFP00000021001
Wingless-type MMTV integration site family, member 2Ba.
    
 0.748
ENSGAFP00000018608
Wingless-type MMTV integration site family, member 3.
    
 0.738
CCH79_00005408
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.738
WNT7A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.689
ENSGAFP00000023449
Wingless-type MMTV integration site family, member 7Ab.
    
 0.689
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
Server load: low (12%) [HD]