Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000001601annotation not available (102 aa)    
Predicted Functional Partners:
CDYL2
Uncharacterized protein.
   
 0.879
ENSGAFP00000005987
Chromodomain protein, Y-like.
   
 0.879
CCH79_00012961
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.817
CCH79_00008175
Cytosine-specific methyltransferase.
    
 0.807
CCH79_00017038
Uncharacterized protein.
   
 0.787
CCH79_00015166
SWIRM domain-containing protein.
   
 
 0.760
ENSGAFP00000020224
Si:dkey-217d24.6.
   
 0.758
CCH79_00014693
Uncharacterized protein.
   
 0.758
CCH79_00016348
Uncharacterized protein.
    
   0.746
ENSGAFP00000004332
HESX homeobox 1.
    
   0.746
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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