Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOMM40LUncharacterized protein. (331 aa)    
Predicted Functional Partners:
TOMM7
Translocase of outer mitochondrial membrane 7.
   
 0.993
CCH79_00001456
Uncharacterized protein.
   
 0.992
ENSGAFP00000026906
Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).
   
 0.991
CCH79_00006422
Protein kinase domain-containing protein.
    
 0.979
CCH79_00015669
Uncharacterized protein.
   
 0.975
ENSGAFP00000007394
annotation not available
    
 0.962
CCH79_00019476
FCP1 homology domain-containing protein.
   
 0.943
CCH79_00006082
Uncharacterized protein.
    
 0.934
ENSGAFP00000014785
Translocase of outer mitochondrial membrane 6 homolog (yeast).
    
 0.929
CCH79_00013093
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
   
  0.907
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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