Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000001693annotation not available (77 aa)    
Predicted Functional Partners:
CCH79_00011836
Uncharacterized protein.
     
 0.741
ENSGAFP00000022498
Lumican.
      
 0.623
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
  
 0.620
CCH79_00004118
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.620
GRIN3A
Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
      
 0.610
CCH79_00007747
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
      
 0.552
ENSGAFP00000015299
Carbonic anhydrase XVI b.
    
 
 0.537
ENSGAFP00000007606
Sprouty homolog 4 (Drosophila).
      
 0.536
CCH79_00009019
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
   
   0.536
RIMS2
Uncharacterized protein.
    
   0.534
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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