STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00015377Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (943 aa)    
Predicted Functional Partners:
ENSGAFP00000003099
annotation not available
    
 0.993
CCH79_00001311
DNA_mis_repair domain-containing protein.
   
 0.988
ENSGAFP00000032183
FA complementation group D2.
    
 0.988
CCH79_00016745
Uncharacterized protein.
   
 0.983
ENSGAFP00000015899
PMS1 homolog 1, mismatch repair system component.
   
 0.937
CCH79_00010005
Uncharacterized protein.
    
 0.885
CCH79_00003036
Lactamase_B domain-containing protein.
    
 0.851
CCH79_00015521
ERCC4 domain-containing protein.
    
 0.849
CCH79_00004523
WW domain-containing protein.
   
 0.833
ENSGAFP00000025186
annotation not available
   
 0.833
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.