Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSGAFP00000001809Helicase, lymphoid specific. (854 aa)    
Predicted Functional Partners:
CCH79_00006176
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
   
 0.985
ENSGAFP00000024675
Polymerase (DNA directed), epsilon 3 (p17 subunit).
    
 0.924
H4C7
H4 clustered histone 7.
   
 0.914
CCH79_00017580
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 
 0.903
CCH79_00000778
POU domain protein.
    
 
 0.895
CCH79_00012037
Protein kinase domain-containing protein.
   
 
 0.887
CCH79_00005389
DNA helicase; Belongs to the MCM family.
   
 
 0.876
CCH79_00007392
Uncharacterized protein.
   
 0.873
CCH79_00009260
Uncharacterized protein.
   
 
 0.872
CCH79_00015844
Uncharacterized protein.
   
 
 0.861
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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