Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00010699Uncharacterized protein. (349 aa)    
Predicted Functional Partners:
CCH79_00008840
CBFD_NFYB_HMF domain-containing protein.
    
 0.999
CCH79_00016086
CBFD_NFYB_HMF domain-containing protein.
   
 0.999
ENSGAFP00000019712
Sp1 transcription factor.
    
 0.974
ENSGAFP00000015861
E1A binding protein p300 b.
    
 0.966
CCH79_00012961
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.964
CCH79_00008794
CBFD_NFYB_HMF domain-containing protein.
    
 0.958
ZHX1
Uncharacterized protein.
    
 
 0.919
CCH79_00000219
Uncharacterized protein.
    
   0.867
CCH79_00009623
Uncharacterized protein.
    
 0.863
CCH79_00018727
Uncharacterized protein.
    
 0.846
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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