Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000001934Ankyrin repeat domain 22. (208 aa)    
Predicted Functional Partners:
ENSGAFP00000001961
Lipase, gastric.
  
 0.700
PDZRN4
PDZ domain containing ring finger 4.
    
 0.696
CCH79_00016464
PDZ domain-containing protein.
    
 0.696
CCH79_00011537
Rhomboid domain-containing protein; Belongs to the peptidase S54 family.
     
 0.690
CCH79_00009715
Uncharacterized protein.
    
 0.672
CCH79_00003780
Uncharacterized protein.
    
 
 0.659
CCH79_00012126
Uncharacterized protein.
      
 0.645
CCH79_00000699
WD_REPEATS_REGION domain-containing protein.
    
 0.634
ENSGAFP00000011427
annotation not available
    
 
 0.624
ENSGAFP00000023426
HIVEP zinc finger 1.
    
 
 0.624
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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