Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000002133annotation not available (219 aa)    
Predicted Functional Partners:
ENSGAFP00000002165
Microtubule actin crosslinking factor 1b.
 
   
 0.705
CCH79_00019129
Uncharacterized protein.
   
 0.700
DSC1
Uncharacterized protein.
   
 0.665
CCH79_00007436
Uncharacterized protein.
   
 0.628
CCH79_00012720
Uncharacterized protein.
   
 0.628
CCH79_00008501
Uncharacterized protein.
   
 0.628
ENY2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.573
PKP1
Uncharacterized protein.
   
 0.570
ENSGAFP00000024210
Plakophilin 1b.
   
 0.570
CCH79_00018419
Uncharacterized protein.
   
 0.570
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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