Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSGAFP00000002255Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. (306 aa)    
Predicted Functional Partners:
ASNA1
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
 0.969
CCH79_00006859
Ubiquitin-like domain-containing protein.
   
 0.943
CCH79_00016371
Uncharacterized protein.
   
 0.935
CCH79_00007687
Uncharacterized protein.
    
 0.920
CCH79_00018543
Uncharacterized protein.
   
 0.914
CLPB
ANK_REP_REGION domain-containing protein.
  
 
 0.851
CCH79_00004963
MPN domain-containing protein.
  
  0.838
CCH79_00004433
Uncharacterized protein.
  
 0.835
CCH79_00003645
Uncharacterized protein.
    
 0.826
CCH79_00008238
Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
   
   0.823
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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