STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00018313Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)    
Predicted Functional Partners:
CCH79_00018468
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
  
 0.974
CCH79_00008259
Uncharacterized protein.
  
 0.963
CCH79_00008918
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.955
CCH79_00010825
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.953
CCH79_00015277
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
0.953
ENSGAFP00000018153
Cytochrome P450, family 3, subfamily c, polypeptide 1.
  
0.950
ENSGAFP00000018507
annotation not available
  
 0.950
ENSGAFP00000020594
Dehydrogenase/reductase (SDR family) member 11a.
  
 0.950
CCH79_00013821
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.949
CYP19A1
Uncharacterized protein.
  
 
0.947
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.