STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00000653Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2225 aa)    
Predicted Functional Partners:
CCH79_00004429
Uncharacterized protein.
   
 0.997
CCH79_00014551
Ca_chan_IQ domain-containing protein.
  
  
 
0.917
RASGRP2
Uncharacterized protein.
   
 
  0.886
CCH79_00018824
Uncharacterized protein.
   
 
  0.886
ENSGAFP00000023392
annotation not available
   
 
  0.886
RASGRP1
Uncharacterized protein.
   
 
  0.886
CCH79_00012223
Uncharacterized protein.
   
 
  0.825
CCH79_00007053
Uncharacterized protein.
   
 
  0.825
CCH79_00014598
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.808
CCH79_00015923
GuKc domain-containing protein.
   
 0.804
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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