STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00014137RING-type domain-containing protein. (701 aa)    
Predicted Functional Partners:
CCH79_00012070
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.853
CCH79_00001531
Uncharacterized protein.
   
 0.851
ENSGAFP00000032292
OS9 endoplasmic reticulum lectin.
   
 0.851
CCH79_00013274
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.836
ENSGAFP00000009399
Derlin 3.
    
 0.836
CCH79_00000107
Fibronectin type-II domain-containing protein.
    
 0.824
CCH79_00000715
LisH domain-containing protein.
   
 0.808
CCH79_00019425
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.784
CCH79_00006093
Uncharacterized protein.
    
 0.777
CCH79_00010258
Uncharacterized protein.
    
 0.777
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.