STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000003551annotation not available (51 aa)    
Predicted Functional Partners:
CCH79_00018468
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 
 0.964
CCH79_00017363
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.955
CCH79_00020893
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.954
CCH79_00015277
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
     
 0.954
CCH79_00018313
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
 0.953
CCH79_00007600
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
 0.953
CCH79_00018243
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
 0.953
CCH79_00006191
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.950
CCH79_00007405
FAD-binding PCMH-type domain-containing protein.
     
 0.940
CCH79_00020063
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
     
 0.940
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.