OTP-2 protein (Gambusia affinis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OTP-2

Uncharacterized protein. (314 aa)

Predicted Functional Partners:

CCH79_00006006

0.595

CCH79_00002845

0.593

CCH79_00001432

0.578

ENSGAFP00000019975

0.578

CCH79_00018850

0.549

CCH79_00001627

0.525

CCH79_00012715

0.525

CCH79_00005561

0.525

LHX3

0.485

ENSGAFP00000021417

0.473

Your Current Organism:

Gambusia affinis

NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCH79_00001432	ENSGAFP00000019975	ENSGAFP00000006355	ENSGAFP00000019975	MADS-box domain-containing protein.	annotation not available	0.894
CCH79_00001432	OTP-2	ENSGAFP00000006355	ENSGAFP00000004134	MADS-box domain-containing protein.	Uncharacterized protein.	0.578
CCH79_00001627	CCH79_00018850	ENSGAFP00000013620	ENSGAFP00000029362	LID domain-containing protein.	BHLH domain-containing protein.	0.612
CCH79_00001627	ENSGAFP00000021417	ENSGAFP00000013620	ENSGAFP00000021417	LID domain-containing protein.	LIM homeobox 4.	0.737
CCH79_00001627	LHX3	ENSGAFP00000013620	ENSGAFP00000017031	LID domain-containing protein.	Uncharacterized protein.	0.737
CCH79_00001627	OTP-2	ENSGAFP00000013620	ENSGAFP00000004134	LID domain-containing protein.	Uncharacterized protein.	0.525
CCH79_00002845	OTP-2	ENSGAFP00000013068	ENSGAFP00000004134	Uncharacterized protein.	Uncharacterized protein.	0.593
CCH79_00005561	CCH79_00018850	ENSGAFP00000025425	ENSGAFP00000029362	LID domain-containing protein.	BHLH domain-containing protein.	0.612
CCH79_00005561	ENSGAFP00000021417	ENSGAFP00000025425	ENSGAFP00000021417	LID domain-containing protein.	LIM homeobox 4.	0.737
CCH79_00005561	LHX3	ENSGAFP00000025425	ENSGAFP00000017031	LID domain-containing protein.	Uncharacterized protein.	0.737
CCH79_00005561	OTP-2	ENSGAFP00000025425	ENSGAFP00000004134	LID domain-containing protein.	Uncharacterized protein.	0.525
CCH79_00006006	OTP-2	ENSGAFP00000011479	ENSGAFP00000004134	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Uncharacterized protein.	0.595
CCH79_00012715	CCH79_00018850	ENSGAFP00000016500	ENSGAFP00000029362	LID domain-containing protein.	BHLH domain-containing protein.	0.612
CCH79_00012715	ENSGAFP00000021417	ENSGAFP00000016500	ENSGAFP00000021417	LID domain-containing protein.	LIM homeobox 4.	0.737
CCH79_00012715	LHX3	ENSGAFP00000016500	ENSGAFP00000017031	LID domain-containing protein.	Uncharacterized protein.	0.737
CCH79_00012715	OTP-2	ENSGAFP00000016500	ENSGAFP00000004134	LID domain-containing protein.	Uncharacterized protein.	0.525
CCH79_00018850	CCH79_00001627	ENSGAFP00000029362	ENSGAFP00000013620	BHLH domain-containing protein.	LID domain-containing protein.	0.612
CCH79_00018850	CCH79_00005561	ENSGAFP00000029362	ENSGAFP00000025425	BHLH domain-containing protein.	LID domain-containing protein.	0.612
CCH79_00018850	CCH79_00012715	ENSGAFP00000029362	ENSGAFP00000016500	BHLH domain-containing protein.	LID domain-containing protein.	0.612
CCH79_00018850	OTP-2	ENSGAFP00000029362	ENSGAFP00000004134	BHLH domain-containing protein.	Uncharacterized protein.	0.549