ENSGAFP00000004411 protein (Gambusia affinis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSGAFP00000004411

Cyclin-dependent kinase 4. (302 aa)

Predicted Functional Partners:

CCH79_00018036

0.991

CCH79_00007041

0.988

ENSGAFP00000032084

0.987

CCH79_00014007

0.985

ENSGAFP00000020448

0.984

CCH79_00012996

0.984

ENSGAFP00000032094

0.983

CCH79_00007165

0.979

CCH79_00008073

0.975

CCH79_00002028

0.970

Your Current Organism:

Gambusia affinis

NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCH79_00002028	CCH79_00007041	ENSGAFP00000008253	ENSGAFP00000002141	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.452
CCH79_00002028	CCH79_00008073	ENSGAFP00000008253	ENSGAFP00000016426	Uncharacterized protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.962
CCH79_00002028	CCH79_00012996	ENSGAFP00000008253	ENSGAFP00000021238	Uncharacterized protein.	Cyclin N-terminal domain-containing protein.	0.970
CCH79_00002028	CCH79_00014007	ENSGAFP00000008253	ENSGAFP00000008697	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.516
CCH79_00002028	CCH79_00018036	ENSGAFP00000008253	ENSGAFP00000004574	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.970
CCH79_00002028	ENSGAFP00000004411	ENSGAFP00000008253	ENSGAFP00000004411	Uncharacterized protein.	Cyclin-dependent kinase 4.	0.970
CCH79_00002028	ENSGAFP00000020448	ENSGAFP00000008253	ENSGAFP00000020448	Uncharacterized protein.	Cyclin D2, b.	0.970
CCH79_00002028	ENSGAFP00000032084	ENSGAFP00000008253	ENSGAFP00000032084	Uncharacterized protein.	Cyclin D3.	0.962
CCH79_00002028	ENSGAFP00000032094	ENSGAFP00000008253	ENSGAFP00000032094	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 1A.	0.749
CCH79_00007041	CCH79_00002028	ENSGAFP00000002141	ENSGAFP00000008253	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.452
CCH79_00007041	CCH79_00008073	ENSGAFP00000002141	ENSGAFP00000016426	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.978
CCH79_00007041	CCH79_00012996	ENSGAFP00000002141	ENSGAFP00000021238	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cyclin N-terminal domain-containing protein.	0.978
CCH79_00007041	CCH79_00018036	ENSGAFP00000002141	ENSGAFP00000004574	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.978
CCH79_00007041	ENSGAFP00000004411	ENSGAFP00000002141	ENSGAFP00000004411	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cyclin-dependent kinase 4.	0.988
CCH79_00007041	ENSGAFP00000020448	ENSGAFP00000002141	ENSGAFP00000020448	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cyclin D2, b.	0.978
CCH79_00007041	ENSGAFP00000032084	ENSGAFP00000002141	ENSGAFP00000032084	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cyclin D3.	0.978
CCH79_00007041	ENSGAFP00000032094	ENSGAFP00000002141	ENSGAFP00000032094	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cyclin-dependent kinase inhibitor 1A.	0.722
CCH79_00007165	CCH79_00008073	ENSGAFP00000023257	ENSGAFP00000016426	ANK_REP_REGION domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.958
CCH79_00007165	CCH79_00012996	ENSGAFP00000023257	ENSGAFP00000021238	ANK_REP_REGION domain-containing protein.	Cyclin N-terminal domain-containing protein.	0.973
CCH79_00007165	CCH79_00014007	ENSGAFP00000023257	ENSGAFP00000008697	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.479