Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSGAFP00000004441Biorientation of chromosomes in cell division 1. (162 aa)    
Predicted Functional Partners:
ENSGAFP00000002795
Retinoblastoma binding protein 5.
    
 0.885
CCH79_00001264
B30.2/SPRY domain-containing protein.
    
 0.884
ENSGAFP00000013096
annotation not available
    
 0.839
ENSGAFP00000013366
CXXC finger protein 1b.
    
 0.839
CCH79_00000699
WD_REPEATS_REGION domain-containing protein.
   
  0.822
CCH79_00008630
Sialidase domain-containing protein.
  
 0.765
CCH79_00005722
tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.757
CCH79_00016647
MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
   0.744
CCH79_00000870
Uncharacterized protein.
    
 0.684
CCH79_00006765
Uncharacterized protein.
    
 0.684
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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