STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00000674Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (552 aa)    
Predicted Functional Partners:
ENSGAFP00000001961
Lipase, gastric.
  
 
 0.916
CCH79_00017957
Hydrolase_4 domain-containing protein.
    
 0.912
CCH79_00007184
PLAT domain-containing protein.
    
  0.910
CCH79_00010418
PLAT domain-containing protein.
    
  0.910
CCH79_00020063
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
  
  
 
0.907
CCH79_00007405
FAD-binding PCMH-type domain-containing protein.
    
 0.904
ENSGAFP00000001810
Phospholipid phosphatase 5.
     
 0.903
CCH79_00001303
acidPPc domain-containing protein.
     
 0.903
CCH79_00007185
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
    
  0.900
CCH79_00009052
PLAT domain-containing protein.
    
  0.900
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.