STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (441 aa)    
Predicted Functional Partners:
CCH79_00011859
CID domain-containing protein.
    
 0.999
CCH79_00005683
RRM domain-containing protein.
   
 0.991
CCH79_00012411
Fip1 domain-containing protein.
    
 0.971
CCH79_00010494
Suf domain-containing protein.
    
 0.964
CCH79_00013138
Uncharacterized protein.
    
 
 0.960
CCH79_00000499
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.948
CCH79_00013693
Uncharacterized protein.
    
 0.946
CCH79_00008580
CPSF_A domain-containing protein.
   
 0.929
ENSGAFP00000028958
TSEN2 tRNA splicing endonuclease subunit.
    
 0.922
YTHDC2
Uncharacterized protein.
   
 0.911
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.