STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00004109HECT domain-containing protein. (1081 aa)    
Predicted Functional Partners:
ENSGAFP00000008603
Thyroid hormone receptor interactor 12.
   
 
0.861
ENSGAFP00000011060
annotation not available
   
 0.849
CCH79_00004963
MPN domain-containing protein.
   
 
 0.828
CCH79_00006985
HECT domain-containing protein.
   
 
0.770
CCH79_00000140
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.724
CCH79_00012188
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 
 0.722
CCH79_00005422
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.702
CCH79_00001659
Uncharacterized protein.
   
 0.700
ENSGAFP00000005310
annotation not available
   
 0.691
CCH79_00012896
Ubiquitin-like domain-containing protein.
   
 0.691
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
Server load: medium (60%) [HD]