STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_000171931-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1095 aa)    
Predicted Functional Partners:
CCH79_00008984
Uncharacterized protein.
    
 0.964
ENSGAFP00000005850
Si:ch211-160o17.2.
     
 0.953
CCH79_00014500
Uncharacterized protein.
     
 0.952
CCH79_00001940
G_PROTEIN_RECEP_F3_4 domain-containing protein.
     
 0.951
ENSGAFP00000002991
Inositol 1,4,5-trisphosphate receptor, type 1a.
   
 0.946
ENSGAFP00000012721
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 0.946
CCH79_00009995
Uncharacterized protein.
   
 0.946
ENSGAFP00000028321
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.945
CCH79_00007195
Uncharacterized protein.
    
 0.943
CCH79_00008985
Uncharacterized protein.
    
 0.942
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
Server load: medium (80%) [HD]