CCH79_00020753 protein (Gambusia affinis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CCH79_00020753

Uncharacterized protein. (111 aa)

Predicted Functional Partners:

CCH79_00001231

0.543

CCH79_00014358

0.543

CCH79_00001607

0.543

ASNA1

0.543

CCH79_00016449

0.481

CCH79_00017514

0.412

CCH79_00016589

0.407

CCH79_00000405

0.400

Your Current Organism:

Gambusia affinis

NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASNA1	CCH79_00001231	ENSGAFP00000020444	ENSGAFP00000008131	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	TPR_REGION domain-containing protein.	0.543
ASNA1	CCH79_00014358	ENSGAFP00000020444	ENSGAFP00000009164	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	RNA_GG_bind domain-containing protein.	0.526
ASNA1	CCH79_00017514	ENSGAFP00000020444	ENSGAFP00000001547	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	AAA domain-containing protein.	0.489
ASNA1	CCH79_00020753	ENSGAFP00000020444	ENSGAFP00000005428	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Uncharacterized protein.	0.543
CCH79_00000405	CCH79_00020753	ENSGAFP00000018372	ENSGAFP00000005428	Uncharacterized protein.	Uncharacterized protein.	0.400
CCH79_00001231	ASNA1	ENSGAFP00000008131	ENSGAFP00000020444	TPR_REGION domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.543
CCH79_00001231	CCH79_00014358	ENSGAFP00000008131	ENSGAFP00000009164	TPR_REGION domain-containing protein.	RNA_GG_bind domain-containing protein.	0.543
CCH79_00001231	CCH79_00020753	ENSGAFP00000008131	ENSGAFP00000005428	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.543
CCH79_00001607	CCH79_00016449	ENSGAFP00000012969	ENSGAFP00000002807	DUF4585 domain-containing protein.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.481
CCH79_00001607	CCH79_00020753	ENSGAFP00000012969	ENSGAFP00000005428	DUF4585 domain-containing protein.	Uncharacterized protein.	0.543
CCH79_00014358	ASNA1	ENSGAFP00000009164	ENSGAFP00000020444	RNA_GG_bind domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.526
CCH79_00014358	CCH79_00001231	ENSGAFP00000009164	ENSGAFP00000008131	RNA_GG_bind domain-containing protein.	TPR_REGION domain-containing protein.	0.543
CCH79_00014358	CCH79_00017514	ENSGAFP00000009164	ENSGAFP00000001547	RNA_GG_bind domain-containing protein.	AAA domain-containing protein.	0.400
CCH79_00014358	CCH79_00020753	ENSGAFP00000009164	ENSGAFP00000005428	RNA_GG_bind domain-containing protein.	Uncharacterized protein.	0.543
CCH79_00016449	CCH79_00001607	ENSGAFP00000002807	ENSGAFP00000012969	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	DUF4585 domain-containing protein.	0.481
CCH79_00016449	CCH79_00020753	ENSGAFP00000002807	ENSGAFP00000005428	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	Uncharacterized protein.	0.481
CCH79_00016589	CCH79_00020753	ENSGAFP00000005249	ENSGAFP00000005428	Uncharacterized protein.	Uncharacterized protein.	0.407
CCH79_00017514	ASNA1	ENSGAFP00000001547	ENSGAFP00000020444	AAA domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.489
CCH79_00017514	CCH79_00014358	ENSGAFP00000001547	ENSGAFP00000009164	AAA domain-containing protein.	RNA_GG_bind domain-containing protein.	0.400
CCH79_00017514	CCH79_00020753	ENSGAFP00000001547	ENSGAFP00000005428	AAA domain-containing protein.	Uncharacterized protein.	0.412