STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000005769NGFI-A binding protein 2 (EGR1 binding protein 2). (499 aa)    
Predicted Functional Partners:
CCH79_00016706
Uncharacterized protein.
   
 0.905
CCH79_00006854
Uncharacterized protein.
   
 0.816
CCH79_00006026
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
   
 0.810
CCH79_00014152
Uncharacterized protein.
   
 0.732
CCH79_00012911
Uncharacterized protein.
   
 0.732
CCH79_00005295
Uncharacterized protein.
   
 0.732
CCH79_00010933
Uncharacterized protein.
   
 0.732
ENSGAFP00000022711
annotation not available
   
 0.732
ENSGAFP00000022717
annotation not available
   
 0.732
ENSGAFP00000022721
annotation not available
   
 0.716
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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