STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAFP00000006132F-box DNA helicase 1. (1054 aa)    
Predicted Functional Partners:
ENSGAFP00000003099
annotation not available
    
 
 0.998
CCH79_00002477
Uncharacterized protein; Belongs to the SKP1 family.
    
 
 0.988
CCH79_00012221
Uncharacterized protein.
  
 0.983
CCH79_00008724
Uncharacterized protein.
  
 0.983
CCH79_00013601
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.978
CCH79_00007041
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.971
CCH79_00017580
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 
 0.966
CCH79_00011934
RECA_2 domain-containing protein.
  
 
 0.960
CCH79_00020571
RECA_2 domain-containing protein.
  
 
 0.959
ENSGAFP00000032169
RAD18 E3 ubiquitin protein ligase.
    
 
 0.937
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.