STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTCBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa)    
Predicted Functional Partners:
CCH79_00000057
Uncharacterized protein.
   
 0.986
CCH79_00004608
Archease domain-containing protein.
  
 0.976
CCH79_00018846
Uncharacterized protein.
   
 0.969
CCH79_00002607
Uncharacterized protein.
    
 0.966
CCH79_00004742
Uncharacterized protein.
    
 0.959
ENSGAFP00000017511
RNA 3'-terminal phosphate cyclase.
  
  
 0.911
CCH79_00009405
MCC-bdg_PDZ domain-containing protein.
  
  
 0.878
CCH79_00000782
Uncharacterized protein.
  
  
 0.878
CCH79_00006099
eRF1_1 domain-containing protein.
  
    0.831
EIF3L
Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
    0.782
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.