BMT2 protein (Gambusia affinis) - STRING interaction network

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BMT2

S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (394 aa)

Predicted Functional Partners:

CCH79_00013576

0.851

CCH79_00019323

0.851

CCH79_00017772

0.835

CCH79_00014927

0.822

CCH79_00017367

0.816

CCH79_00014533

0.796

CCH79_00004759

0.796

CCH79_00008086

0.793

CCH79_00009905

0.793

CCH79_00017490

0.793

Your Current Organism:

Gambusia affinis

NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	CCH79_00004759	ENSGAFP00000006709	ENSGAFP00000029166	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.796
BMT2	CCH79_00008086	ENSGAFP00000006709	ENSGAFP00000017003	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.793
BMT2	CCH79_00009905	ENSGAFP00000006709	ENSGAFP00000017355	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.793
BMT2	CCH79_00013576	ENSGAFP00000006709	ENSGAFP00000006745	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.851
BMT2	CCH79_00014533	ENSGAFP00000006709	ENSGAFP00000005095	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.796
BMT2	CCH79_00014927	ENSGAFP00000006709	ENSGAFP00000024092	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Uncharacterized protein.	0.822
BMT2	CCH79_00017367	ENSGAFP00000006709	ENSGAFP00000022403	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain-containing protein.	0.816
BMT2	CCH79_00017490	ENSGAFP00000006709	ENSGAFP00000028634	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.793
BMT2	CCH79_00017772	ENSGAFP00000006709	ENSGAFP00000030961	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Uncharacterized protein.	0.835
BMT2	CCH79_00019323	ENSGAFP00000006709	ENSGAFP00000008065	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.851
CCH79_00004759	BMT2	ENSGAFP00000029166	ENSGAFP00000006709	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.796
CCH79_00004759	CCH79_00008086	ENSGAFP00000029166	ENSGAFP00000017003	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.954
CCH79_00004759	CCH79_00009905	ENSGAFP00000029166	ENSGAFP00000017355	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.954
CCH79_00004759	CCH79_00013576	ENSGAFP00000029166	ENSGAFP00000006745	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.955
CCH79_00004759	CCH79_00014533	ENSGAFP00000029166	ENSGAFP00000005095	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.887
CCH79_00004759	CCH79_00017490	ENSGAFP00000029166	ENSGAFP00000028634	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.954
CCH79_00004759	CCH79_00019323	ENSGAFP00000029166	ENSGAFP00000008065	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.948
CCH79_00008086	BMT2	ENSGAFP00000017003	ENSGAFP00000006709	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.793
CCH79_00008086	CCH79_00004759	ENSGAFP00000017003	ENSGAFP00000029166	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.954
CCH79_00008086	CCH79_00009905	ENSGAFP00000017003	ENSGAFP00000017355	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.892

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