STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00012380Protein kinase domain-containing protein. (513 aa)    
Predicted Functional Partners:
CCH79_00004726
Uncharacterized protein; Belongs to the calmodulin family.
   
 0.954
ENSGAFP00000017869
Calmodulin 3b (phosphorylase kinase, delta).
   
 0.954
ENSGAFP00000028964
annotation not available
   
 0.954
ENSGAFP00000005723
Calmodulin-like 4a.
    
 0.940
ENSGAFP00000018185
Ryanodine receptor 2b (cardiac).
    
 0.907
RYR2
Uncharacterized protein.
    
 0.906
CCH79_00020153
Phosphoinositide phospholipase C.
    
 0.900
CCH79_00006731
Phosphoinositide phospholipase C.
    
 0.900
CCH79_00013516
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.898
CCH79_00017193
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.897
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.