STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00004894Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (169 aa)    
Predicted Functional Partners:
CCH79_00007766
Uncharacterized protein.
   
    0.999
ENSGAFP00000021490
Biogenesis of lysosomal organelles complex-1, subunit 1.
    
 0.986
CCH79_00008771
Uncharacterized protein.
    
 0.983
CCH79_00008768
Uncharacterized protein.
   
 0.956
ENSGAFP00000014686
Biogenesis of lysosomal organelles complex-1, subunit 3.
    
 0.942
CCH79_00020009
Uncharacterized protein.
    
 0.886
CCH79_00018803
Uncharacterized protein.
    
 0.841
CCH79_00007399
Uncharacterized protein.
    
 
 0.803
ENSGAFP00000031969
Zgc:162344.
   
    0.751
CCH79_00017034
RTR1-type domain-containing protein.
   
    0.742
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.