STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH79_00013257ANK_REP_REGION domain-containing protein. (594 aa)    
Predicted Functional Partners:
CCH79_00003046
Uncharacterized protein.
   
 0.944
CCH79_00016011
Uncharacterized protein.
    
 0.911
CCH79_00003838
Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.
  
 0.887
CCH79_00004039
Uncharacterized protein.
    
 0.886
CCH79_00011010
FHA domain-containing protein.
    
 0.875
ENSGAFP00000007269
RAD50 homolog, double strand break repair protein.
    
 0.824
CCH79_00012146
Tower domain-containing protein.
    
 0.818
CCH79_00017580
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.818
ENSGAFP00000021072
Ribosomal protein S27a.
    
  0.809
ENSGAFP00000006885
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.800
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.