STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSGEPProbable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (335 aa)    
Predicted Functional Partners:
ENSGAFP00000012290
TP53 regulating kinase.
  
 0.998
CCH79_00014385
Uncharacterized protein; Belongs to the CGI121/TPRKB family.
    
 0.998
ENSGAFP00000011002
Si:ch211-153b23.4.
  
 
 0.906
CCH79_00011508
YrdC-like domain-containing protein.
  
 
 0.906
CCH79_00000368
LMWPc domain-containing protein.
    
 0.842
CCH79_00003126
Uncharacterized protein.
    
 0.759
ENSGAFP00000008287
CoA synthase.
    
 0.759
CCH79_00004814
Uncharacterized protein.
  
 
 0.735
CCH79_00013123
Uncharacterized protein.
    
 0.732
CCH79_00013788
Peptidase_M22 domain-containing protein.
    
 
0.683
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
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