Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Neut_0776KEGG: neu:NE1470 hypothetical protein. (126 aa)    
Predicted Functional Partners:
Neut_1363
PFAM: Propeptide, PepSY amd peptidase M4; KEGG: neu:NE1410 hypothetical protein.
  
    0.909
thrB
Homoserine kinase; KEGG: neu:NE1471 putative homoserine kinase protein; TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family.
  
    0.778
Neut_0318
Kef-type potassium/proton antiporter, CPA2 family; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: noc:Noc_2952 sodium/hydrogen exchanger, TrkA-N; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
    0.769
Neut_0777
PFAM: conserved hypothetical protein 730; KEGG: neu:NE1469 hypothetical protein; Belongs to the LOG family.
       0.658
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.630
Neut_0774
KEGG: neu:NE1472 possible transmembrane protein.
 
     0.600
Neut_1784
KEGG: neu:NE2330 sigma-E factor negative regulatory protein RseA.
  
     0.554
Neut_0548
Conserved hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.518
Neut_1232
KEGG: neu:NE0503 hypothetical protein.
  
     0.491
Neut_0497
TIGRFAM: TonB family protein; KEGG: neu:NE1626 putative TonB protein.
  
     0.479
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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