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dut protein (Nitrosomonas eutropha) - STRING interaction network
"dut" - Deoxyuridine 5'-triphosphate nucleotidohydrolase in Nitrosomonas eutropha
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
dutDeoxyuridine 5’-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (149 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
   
  0.990
Neut_2467
Ribonucleotide-diphosphate reductase subunit alpha (957 aa)
   
 
  0.980
Neut_0002
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (373 aa)
   
 
  0.979
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (215 aa)
   
 
  0.963
Neut_0783
Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase (401 aa)
 
        0.942
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (141 aa)
     
 
    0.911
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (247 aa)
     
 
  0.905
dcd
Deoxycytidine triphosphate deaminase (188 aa)
         
  0.902
Neut_2468
Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (377 aa)
   
   
  0.897
Neut_0785
Hypothetical protein (141 aa)
              0.860
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha, N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha Koops et al. 2001, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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